Review





Similar Products

btbr t + itpr3 tf /j mice  (Jackson Laboratory)
90
Jackson Laboratory btbr t + itpr3 tf /j mice
Btbr T + Itpr3 Tf /J Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr t + itpr3 tf /j mice/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr t + itpr3 tf /j mice - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr t + itpr3tf/j mice  (Jackson Laboratory)
90
Jackson Laboratory btbr t + itpr3tf/j mice
Btbr T + Itpr3tf/J Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr t + itpr3tf/j mice/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr t + itpr3tf/j mice - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr ob/ob mice btbr.cg-lepob/wiscj  (Jackson Laboratory)
90
Jackson Laboratory btbr ob/ob mice btbr.cg-lepob/wiscj
Pancreatic islet analysis. A Representative hematoxylin–eosin (HE) staining for morphological evaluation of pancreatic islets at 14–15 and 18–20 weeks of age. B Pancreatic islet area analysis across experimental groups. (* p < 0.05). C Spearman correlation between islets’ area (µm 2 ) and body weight (g). D Representative images for insulin immunohistochemical analysis. E Quantification of insulin-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. <t>BTBR</t> ob/ob ; # vs. SGLT2i; & vs. SGLT2i + CR; $ vs. SGLT2i + CR + BM-MSCs; continuous line indicated difference between time points). Scale bars represent 100 μm in A and D . Error bars represent mean ± SEM; n = 6 animals
Btbr Ob/Ob Mice Btbr.Cg Lepob/Wiscj, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr ob/ob mice btbr.cg-lepob/wiscj/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr ob/ob mice btbr.cg-lepob/wiscj - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr t+itpr3tf/j mice  (Jackson Laboratory)
90
Jackson Laboratory btbr t+itpr3tf/j mice
Pancreatic islet analysis. A Representative hematoxylin–eosin (HE) staining for morphological evaluation of pancreatic islets at 14–15 and 18–20 weeks of age. B Pancreatic islet area analysis across experimental groups. (* p < 0.05). C Spearman correlation between islets’ area (µm 2 ) and body weight (g). D Representative images for insulin immunohistochemical analysis. E Quantification of insulin-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. <t>BTBR</t> ob/ob ; # vs. SGLT2i; & vs. SGLT2i + CR; $ vs. SGLT2i + CR + BM-MSCs; continuous line indicated difference between time points). Scale bars represent 100 μm in A and D . Error bars represent mean ± SEM; n = 6 animals
Btbr T+Itpr3tf/J Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr t+itpr3tf/j mice/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr t+itpr3tf/j mice - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr t+ itpr3tf/j mice  (Jackson Laboratory)
90
Jackson Laboratory btbr t+ itpr3tf/j mice
Pancreatic islet analysis. A Representative hematoxylin–eosin (HE) staining for morphological evaluation of pancreatic islets at 14–15 and 18–20 weeks of age. B Pancreatic islet area analysis across experimental groups. (* p < 0.05). C Spearman correlation between islets’ area (µm 2 ) and body weight (g). D Representative images for insulin immunohistochemical analysis. E Quantification of insulin-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. <t>BTBR</t> ob/ob ; # vs. SGLT2i; & vs. SGLT2i + CR; $ vs. SGLT2i + CR + BM-MSCs; continuous line indicated difference between time points). Scale bars represent 100 μm in A and D . Error bars represent mean ± SEM; n = 6 animals
Btbr T+ Itpr3tf/J Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr t+ itpr3tf/j mice/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr t+ itpr3tf/j mice - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr t+ltpr3tf/j mice  (Jackson Laboratory)
90
Jackson Laboratory btbr t+ltpr3tf/j mice
Pancreatic islet analysis. A Representative hematoxylin–eosin (HE) staining for morphological evaluation of pancreatic islets at 14–15 and 18–20 weeks of age. B Pancreatic islet area analysis across experimental groups. (* p < 0.05). C Spearman correlation between islets’ area (µm 2 ) and body weight (g). D Representative images for insulin immunohistochemical analysis. E Quantification of insulin-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. <t>BTBR</t> ob/ob ; # vs. SGLT2i; & vs. SGLT2i + CR; $ vs. SGLT2i + CR + BM-MSCs; continuous line indicated difference between time points). Scale bars represent 100 μm in A and D . Error bars represent mean ± SEM; n = 6 animals
Btbr T+Ltpr3tf/J Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr t+ltpr3tf/j mice/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr t+ltpr3tf/j mice - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr mice btbr t + itpr3/j  (Jackson Laboratory)
90
Jackson Laboratory btbr mice btbr t + itpr3/j
Pancreatic islet analysis. A Representative hematoxylin–eosin (HE) staining for morphological evaluation of pancreatic islets at 14–15 and 18–20 weeks of age. B Pancreatic islet area analysis across experimental groups. (* p < 0.05). C Spearman correlation between islets’ area (µm 2 ) and body weight (g). D Representative images for insulin immunohistochemical analysis. E Quantification of insulin-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. <t>BTBR</t> ob/ob ; # vs. SGLT2i; & vs. SGLT2i + CR; $ vs. SGLT2i + CR + BM-MSCs; continuous line indicated difference between time points). Scale bars represent 100 μm in A and D . Error bars represent mean ± SEM; n = 6 animals
Btbr Mice Btbr T + Itpr3/J, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr mice btbr t + itpr3/j/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr mice btbr t + itpr3/j - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr- pah enu2 /j mice  (Jackson Laboratory)
90
Jackson Laboratory btbr- pah enu2 /j mice
Differential transduction efficiencies in male vs. female Pah <t>enu2</t> mice dosed IV with either OXB-401 or OXB-Null. Median VCN is shown for each group at day 85 post dosing. No significant differences were observed between the groups (p > 0.05).
Btbr Pah Enu2 /J Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr- pah enu2 /j mice/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr- pah enu2 /j mice - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
btbr mice  (Jackson Laboratory)
90
Jackson Laboratory btbr mice
Differential transduction efficiencies in male vs. female Pah <t>enu2</t> mice dosed IV with either OXB-401 or OXB-Null. Median VCN is shown for each group at day 85 post dosing. No significant differences were observed between the groups (p > 0.05).
Btbr Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/btbr mice/product/Jackson Laboratory
Average 90 stars, based on 1 article reviews
btbr mice - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


Pancreatic islet analysis. A Representative hematoxylin–eosin (HE) staining for morphological evaluation of pancreatic islets at 14–15 and 18–20 weeks of age. B Pancreatic islet area analysis across experimental groups. (* p < 0.05). C Spearman correlation between islets’ area (µm 2 ) and body weight (g). D Representative images for insulin immunohistochemical analysis. E Quantification of insulin-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. BTBR ob/ob ; # vs. SGLT2i; & vs. SGLT2i + CR; $ vs. SGLT2i + CR + BM-MSCs; continuous line indicated difference between time points). Scale bars represent 100 μm in A and D . Error bars represent mean ± SEM; n = 6 animals

Journal: Stem Cell Research & Therapy

Article Title: Combining sodium-glucose co-transporter-2 inhibitor with mesenchymal stem cells and brown adipose tissue (BAT) and white adipose tissue (WAT) transplantation to mitigate the progression of diabetic kidney disease: a pre-clinical approach

doi: 10.1186/s13287-025-04358-7

Figure Lengend Snippet: Pancreatic islet analysis. A Representative hematoxylin–eosin (HE) staining for morphological evaluation of pancreatic islets at 14–15 and 18–20 weeks of age. B Pancreatic islet area analysis across experimental groups. (* p < 0.05). C Spearman correlation between islets’ area (µm 2 ) and body weight (g). D Representative images for insulin immunohistochemical analysis. E Quantification of insulin-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. BTBR ob/ob ; # vs. SGLT2i; & vs. SGLT2i + CR; $ vs. SGLT2i + CR + BM-MSCs; continuous line indicated difference between time points). Scale bars represent 100 μm in A and D . Error bars represent mean ± SEM; n = 6 animals

Article Snippet: BTBR ob/ob mice (BTBR.Cg-Lepob/WiscJ; 004824-JAX Laboratories, Bar Harbor, ME, USA), homozygous for leptin gene knockout, serve as a model for T2DM and DKD.

Techniques: Staining, Immunohistochemical staining

Immunohistochemical analysis of pancreatic islets. A Representative images of pancreatic sections from experimental groups stained for cleaved caspase-3 at 14–15 and 18–20 weeks of age. B Quantification of cleaved caspase-3-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. BTBR ob/ob ; continuous line indicates difference between time points). Scale bars represent 100 μm in A . Error bars represent mean ± SEM; n = 5 animals

Journal: Stem Cell Research & Therapy

Article Title: Combining sodium-glucose co-transporter-2 inhibitor with mesenchymal stem cells and brown adipose tissue (BAT) and white adipose tissue (WAT) transplantation to mitigate the progression of diabetic kidney disease: a pre-clinical approach

doi: 10.1186/s13287-025-04358-7

Figure Lengend Snippet: Immunohistochemical analysis of pancreatic islets. A Representative images of pancreatic sections from experimental groups stained for cleaved caspase-3 at 14–15 and 18–20 weeks of age. B Quantification of cleaved caspase-3-positive cells per pancreatic islets across groups. ( p < 0.05; * vs. BTBR ob/ob ; continuous line indicates difference between time points). Scale bars represent 100 μm in A . Error bars represent mean ± SEM; n = 5 animals

Article Snippet: BTBR ob/ob mice (BTBR.Cg-Lepob/WiscJ; 004824-JAX Laboratories, Bar Harbor, ME, USA), homozygous for leptin gene knockout, serve as a model for T2DM and DKD.

Techniques: Immunohistochemical staining, Staining

Gene expression of podocyte markers and components of the RAAS and Ang II/Nox4/TRPC6 axis compared to BTBR wild type. A WT-1. B Nphs1. C Synpo2. D Actn4. E Nox4. F Trpc6. G Ace. H Ace2. I Ace2/Ace ratio. (* p < 0.05). Error bars represent mean ± SEM; n = 5–6 animals

Journal: Stem Cell Research & Therapy

Article Title: Combining sodium-glucose co-transporter-2 inhibitor with mesenchymal stem cells and brown adipose tissue (BAT) and white adipose tissue (WAT) transplantation to mitigate the progression of diabetic kidney disease: a pre-clinical approach

doi: 10.1186/s13287-025-04358-7

Figure Lengend Snippet: Gene expression of podocyte markers and components of the RAAS and Ang II/Nox4/TRPC6 axis compared to BTBR wild type. A WT-1. B Nphs1. C Synpo2. D Actn4. E Nox4. F Trpc6. G Ace. H Ace2. I Ace2/Ace ratio. (* p < 0.05). Error bars represent mean ± SEM; n = 5–6 animals

Article Snippet: BTBR ob/ob mice (BTBR.Cg-Lepob/WiscJ; 004824-JAX Laboratories, Bar Harbor, ME, USA), homozygous for leptin gene knockout, serve as a model for T2DM and DKD.

Techniques: Gene Expression

Differential transduction efficiencies in male vs. female Pah enu2 mice dosed IV with either OXB-401 or OXB-Null. Median VCN is shown for each group at day 85 post dosing. No significant differences were observed between the groups (p > 0.05).

Journal: Experimental Biology and Medicine

Article Title: Gender difference in pre-clinical liver-directed gene therapy with lentiviral vectors

doi: 10.3389/ebm.2025.10422

Figure Lengend Snippet: Differential transduction efficiencies in male vs. female Pah enu2 mice dosed IV with either OXB-401 or OXB-Null. Median VCN is shown for each group at day 85 post dosing. No significant differences were observed between the groups (p > 0.05).

Article Snippet: For the second study, BTBR- Pah enu2 /J mice [ ], also referred to as Pah enu2 ) were obtained from The Jackson Laboratory and dosed IV with TSSM buffer (200 μL), OXB-Null (4 × 10 10 TU/kg) or OXB-401 (4 × 10 10 TU/kg) and observed for the duration of the study (85 days).

Techniques: Transduction